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Hybrid MRI-Radiation Therapy System May Improve Cancer Treatment

By HospiMedica staff writers
Posted on 07 Aug 2007
By combining the high-quality three-dimensional (3D) images of magnetic resonance imaging (MRI) with the intense tumor-killing X-rays of a linear accelerator, scientists are constructing a prototype that could for the first time enable powerful X-ray beams to become an effective treatment option for liver, stomach, and pancreatic cancers, which currently must be treated with surgery, drugs, or internal radioactive seeds, in most instances. More...
The hybrid device could also improve results for all cancer patients receiving radiation therapy.

Using a process called advanced real-time adaptive radiotherapy (ART), the prototype system will allow for near-real-time 3D magnetic resonance imaging (MRI) at the same time radiation is being administered. MRI can provide higher-quality images of tumors and organs than X-rays or computed tomography (CT) machines. Moreover, it is the only imaging technique that can provide high-quality, near-real-time 3D images inside the body.

Combining a linear accelerator used for radiation treatments and an MRI system is complex because they function on incompatible scientific and engineering principles. ART overcomes the issue by rotating an MRI machine and a linear accelerator together. The two machines are fixed with respect to each other and rotate in unison around the patient, obtaining images and delivering radiation treatment from all angles. This fixed-system concept decreases electromagnetic interference between the linear accelerator and MRI.

A finished prototype is expected by December 2007. According to the researchers, from the Alberta Cancer Board (Canada), the machine will improve the effectiveness of treatments for solid tumors, thereby reducing side effects. Furthermore, it could improve treatment for lung and prostate cancers, where it is still difficult to administer enough radiation doses to obtain a better chance of a cure.

The study's findings were presented at the 49th annual meeting of the American Association of Physicists in Medicine (AAPM) on July 22-26, 2007 in Minneapolis, MN, USA.


Related Links:
Alberta Cancer Board

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